SubtiBank SubtiBank
Version comparison:

2018-02-12 18:17:232025-05-14 08:38:34

locus

BSU18090

BSU_18090

geneLength

1965

1968

outlinks

bsu

BSU18090

BSU_18090

Gene

Coordinates

1,933,477 → 1,935,444

1,933,477 1,935,444

Gene

Phenotypes of a mutant

essential [Pubmed|12682299]

essential [Pubmed|12682299]

upon overexpression, topoisomerase IV ([[protein|ParE]]-[[protein|ParC]]) can take over the functions of the type 1A topoisomerases [[protein|TopA]] and [[protein|TopB]] [pubmed|30957856]

The protein

Protein family

type IIA topoisomerase family (according to Swiss-Prot)

type II topoisomerase [[protein|GyrB]] family (together with [[protein|GyrB]]) (according to UniProt)

The protein

Paralogous protein(s)

[[protein|GyrB]]

[[this]]

References

16272394, 9539793, 16267290, 16479537, 23965305, 27120414, 9722641, 12767818

The protein

Catalyzed reaction/ biological activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to UniProt)

Biological materials

lacZ fusion

GP2550 ([[gene|parE]]::lacZ cat, based on [SW|pAC5]), available in [SW|Jörg Stülke]'s lab [pubmed|30957856]

References

Reviews

16936698

References

Original publications

16272394, 9539793, 16267290, 16479537, 23965305, 27120414, 9722641, 12767818, 10713132, 9334322, 8940171, 7590259, 10944214, 1330320, 12857958, 11090135, 8104339, 8227000, 30222737, 30957856